Prof. Anthony J Sinskey

Professor of Biology
Faculty Director, Center for Biomedical Innovation (CBI)
Co-Director, Malaysia-MIT Biotechnology Partnership Programme (MMBPP)

Areas of Interest and Expertise

Microbiology
Biotechnology
Monitoring of Mammalian Cell Growth and Metabolism in High Density Cell Culture
Monitoring of Substrates and End Products for Prediction of Cell Mass, Growth Rate, and Metabolic Pathways
Development of rDNA Technology for Corynebacterium
Biopolymer Engineering
Biodegradable Polymers
Primary Metabolism
Bioengineering
Therapeutic Protein Biotechnology
Bioinformatics and MicroArrays
Cambridge-MIT Institute (CMI)
Biofuels
Food, Safety

Research Summary

We leverage an interdisciplinary approach to metabolic engineering -- focusing on the fundamental physiology, biochemistry and molecular genetics of important organisms to determine key factors that regulate the synthesis of different biomolecules. We support a broad range of interests, examining amino acid metabolism in Corynebacterium glutamicum, bioremediation and bioconversion processes in Rhodococcus, and biopolymer synthesis in Gram-negative bacteria. As for eukaryotic systems, we study both lipid biosynthesis and embryogensis in oil palm, as well as the accumulation of secondary metabolites in tropical plants.

Recent Work