Principal Investigator Richard Schrock
This research involves the application of metathesis reactions in organic chemistry. Most recently the research has focussed on reactions that produce as high as >99% Z products in good yields. Examples include Z-selective coupling of terminal olefins, ethenolysis, cross-metathesis, ring-closing, or alkane metathesis reactions. Applications are focussed on the synthesis of natural products. A recent advance has been the stereoselective (Z) cross metathesis of ordinary olefins with electron poor olefins such as Z 1,2-dichloroethylene or Z-1,1,1,4,4,4-hexafluoroethylene.