Principal Investigator Ron Weiss
Project Website http://groups.csail.mit.edu.ezproxy.canberra.edu.au/synbio/projects/in-vivo-biosensors/
Whether it is a specific cancer cell, stem cell or neuron, each cell state is characterized by a set of biomarkers: mRNA, proteins and microRNA.
We seek to engineer therapeutic and diagnostic genetic circuits that interface with cellular context and perform computation to decide the fate of a cell based on the integration of multiple biomarker sensors.