Principal Investigator Forest White
T cell signaling is another focus area within the lab, specifically aimed (1) at the signaling networks involved in T cell response to peptide ligand stimulation, with the goal of identifying defective signaling processes which may lead to autoimmune disorders such as Type 1 diabetes, and (2) at signaling networks downstream of IL-2, IL-15, CD3, and CD28 stimulation, with the goal of monitoring the network response to combinations of cytokine stimulations.